The Best Joint Supplements on the Market

The Best Joint Supplements on the Market

Joint health is often neglected until it’s too late. Those who experience pain – whether it’s a result of injury, strenuous physical activity or arthritis – know all too well that joint health is a luxury many take for granted.

Although joint pain may feel overwhelming and discouraging at times, there are plenty of supplements that are scientifically proven to relieve pain, reduce inflammation and support overall joint health. Though they may not be a cure-all, they’ll set you on the path to healing and living a healthier, happier life. 

Whether you’re already experiencing joint pain or you’re looking to take preventative measures, we give you the best joint supplements on the market.

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Key Supplements for Joint Health

While there are plenty of joint supplements on the market, many of them don’t contain a complete profile of all of the ingredients that are vital for joint health. Here are the primary supplements to look for when choosing a joint supplement: 

*Note: These can be consumed individually, but buying several different supplements can be pricey. We recommend choosing an all-in-one joint supplement to save money and avoid taking more pills than necessary. 


Glucosamine is a naturally occurring compound in the body. It synthesizes glycosaminoglycans, which are essential for building and restoring ligaments, tendons and cartilage. 

Though your body naturally produces glucosamine, it is often taken as a supplement to reduce joint stiffness and pain, repair damage and increase mobility. Though studies on glucosamine are limited, as it is on many joint health supplements, research suggests that taking it may ease symptoms of osteoarthritis and rheumatoid arthritis. While glucosamine certainly won’t cure joint pain, there is enough evidence that suggests it may be worth a try – especially when paired with other supplements, like chondroitin. 

Potential (though unlikely) side effects include stomach aches, intestinal issues, headaches, drowsiness and rashes. Many glucosamine supplements are derived from shellfish – so, if you have a shellfish allergy, be sure to choose a shellfish-free product.


Like glucosamine, chondroitin is a naturally occurring compound in the body. It is the most abundant glycosaminoglycan in cartilage (a connective tissue that protects your joints and bones), and it helps fight off damaging enzymes. Commonly co-formulated or paired with glucosamine, it is often taken as a supplement to slow cartilage loss and boost resiliency and elasticity. 

Research on chondroitin on its own is limited – however, one study shows that a daily 800mg dose of chondroitin sulfate provides the same pain relief as a 200mg dose of Celebrex, an anti-inflammatory drug used to treat arthritis-related pain. Research also suggests that there may be significant benefits to treating osteoarthritis with a combination of chondroitin and glucosamine. 

Chondroitin is safe to take, although it may cause mild stomach pain, nausea or intestinal issues.

Omega-3 Fatty Acids (Fish Oil)

Many sweeping claims have been made about omega-3 fatty acids (also known as fish oil) over the years. But, no matter the claims made about it, omega-3 is an essential nutrient for proper bodily function. 

Omega-3 fatty acids improve blood vessel function, play a key role in blood clotting and influence gene expression. And, because they help reduce pain and inflammation, many people take them as a supplement to ease the negative impact of arthritis on the joints. One study shows that omega-3 fatty acids may aid in preventing or attenuating arthritis – rheumatoid arthritis, in particular. 

Because omega-3 is derived from fish, it’s not vegan- or vegetarian-friendly – however, algae oil may be a good substitution. If you choose fish or algae supplements, be sure to choose a brand that has been tested for contaminants like mercury. And, because fish oil is blood-thinning, don’t take any more than 3 grams per day. Negative side effects may include an upset stomach, temporary change in taste, high blood sugar, intestinal issues or acid reflux. 


Curcumin is the active ingredient in turmeric, a popular spice used in cooking and a variety of supplement regimens. Curcumin is believed to have anti-inflammatory properties, making it a sought-after choice for those who experience joint pain, stiffness and discomfort. 

Studies show that curcumin can have a favorable impact on osteoarthritis symptoms by significantly improving pain and function and that it may reduce pain in the short term. It also helps preserve joint health by protecting cartilage from degradation. However, curcumin is much more than an anti-inflammatory – it also has strong antioxidant properties and has been known to improve heart health and prevent Alzheimer’s disease.

High doses of curcumin may cause nausea, intestinal issues or stomach ulcers, though these side effects are unlikely. 

MSM (Methylsulfonylmethane)

MSM (short for methylsulfonylmethane) is an organic form of sulfur that is known to reduce pain and swelling. It’s often combined with other supplements, like glucosamine or chondroitin, for increased benefits – but it’s effective on its own, too. 

It’s believed that the sulfur contained in MSM helps ligaments maintain flexibility and strength, although this is backed more by individual success stories than it is by scientific research. However, a study found that MSM supplementation improved inflammation, joint and muscle pain and antioxidant capacity. Like many other effective joint health supplements, MSM inhibits the breakdown of cartilage and promotes longevity.  

MSM can be tolerated at dosages of up to four grams daily. Side effects may include nausea, bloating, intestinal issues and stomach discomfort. 

Vitamin D

From fighting disease to reducing depression, vitamin D – also called the “sunshine vitamin” – has countless use cases. It’s a naturally occurring compound that is crucial for bone health and growth. That said, taking vitamin D on a routine basis may reduce your risk of developing joint pain or arthritis later down the line. 

Research shows that adults over 50 with a vitamin D deficiency are more likely to develop hip and knee pain, and the pain will worsen if the deficiency goes untreated. Another study reveals that those with rheumatoid arthritis had low vitamin D levels. While research on the connection between joint pain and vitamin D is limited, there are countless benefits of taking vitamin D – so it’s a good idea to take it regularly.

The side effects of taking vitamin D include frequent urination, weight loss, nausea, intestinal issues and poor appetite. To avoid experiencing these unfavorable symptoms, avoid taking more than 4,000 IU of vitamin D per day. 


Collagen is the most abundant protein in the human body. It’s the primary component of all connective tissues, including tendons, ligaments, skin and muscles. You can get collagen from foods like pork skin and bone broth, but it’s often taken as a supplement. Most collagen supplements are hydrolyzed, meaning the collagen has been broken down and is easier to absorb. 

As we get older, the amount of collagen in our body decreases. As a result, you’re more likely to lose bone density and develop arthritis or joint pain. Research shows that taking collagen significantly decreases joint stiffness and may lead to lower inflammation, better joint support and reduced pain. It also supports overall joint health by stimulating cartilage regeneration. 

Many collagen supplements are not vegan. So, if you adhere to a vegan diet, be sure to choose a vegan collagen supplement. Side effects may include intestinal issues, allergies and kidney stones. 

Hyaluronic Acid

Hyaluronic acid is a popular skincare ingredient that helps the skin retain moisture and elasticity – but did you know that it can also be taken as a dietary supplement? 

Hyaluronic acid is found in the joints, where it keeps the space between your bones lubricated and allows them to move freely. As a result, your bones are less likely to grind against each other and cause pain. Research shows that taking a hyaluronic acid supplement can significantly reduce osteoarthritis-related pain. It’s also known to delay cartilage degradation and promote the growth of new cells and tissues within the body.

80mg to 200mg of hyaluronic acid per day is enough to reap the benefits. Side effects may include headaches, intestinal issues or vomiting. 

Read more: Do Any Joint Supplements Really Work? 

How to Choose and Use Supplements for Joint Health

With so many supplements on the market, choosing one that suits your needs may feel overwhelming. Here’s how to choose (and use) joint health supplements:

  • Select high-quality supplements. Look for supplements from reputable brands that adhere to good manufacturing practices (GMP) or have third-party certifications like NSF or USP, and be sure to check for quality seals or certifications indicating purity, potency and absence of contaminants. 
  • Consult with your healthcare provider. Before starting any new supplement regimen, speak with your healthcare provider – especially if you have underlying health conditions or if you take medications. A trusted healthcare provider can offer personalized advice and ensure that you aren’t taking any supplements that may cause you harm. 
  • Consider dosage and timing. It’s important to follow dosage and timing recommendations for each supplement, as every supplement is different. Never take more than the recommended dosage unless recommended by a healthcare provider. Keep in mind that factors like time of day and whether or not you’ve eaten can impact how well (or how poorly) your body absorbs the supplement.
  • Be aware of possible interactions with other medications. Some joint supplements may impact the potency or absorption of medications. If you take medication, speak with your doctor before taking any supplements. 
  • Look for combination supplements. There are plenty of joint health supplements on the market that act as an all-in-one. Opting for combination supplements over individual supplements may also have synergistic benefits.
  • Monitor for effectiveness and side effects. Everyone is different, and what works for some may not work for others. Pay close attention to how your body responds to supplements – do you see any improvements? Are you experiencing any negative side effects? Adjust your supplement regimen as needed to find what works best for you.

Lifestyle Factors Supporting Joint Health

Supplements are called “supplements” for a reason – they’re a supplement to a healthy lifestyle, not a cure-all. Here are some important lifestyle factors that are essential in supporting and maintaining joint health:

  • A balanced diet. Our body relies on sufficient nutrition to function properly. Consuming a variety of nutrient-dense foods like fruits, vegetables, lean proteins and healthy fats (foods found on the perimeter of the grocery store) is the best way to support your health. Processed foods, refined sugars and unhealthy fats, on the other hand, may worsen inflammation and exacerbate joint pain. 
  • Hydration. Like a balanced diet, staying hydrated is at the core of overall well-being. Among the countless benefits of drinking plenty of water is proper joint lubrication. A good rule of thumb is to drink about an ounce of water for each pound you weigh.
  • Regular exercise. Although joint pain may stifle your ability to complete high-intensity workouts, gentle, low-impact exercise will do the trick. Regular physical activity like yoga, swimming, cycling or a brisk walk will strengthen your muscles, improve cardiovascular health and maintain joint mobility. 
  • Maintaining a healthy weight. Maintaining a healthy weight will reduce the load that your joints take on – especially joints that bear most of your weight, like your hips and knees. 
  • Proper posture and body mechanics. Practicing good posture and being mindful of the way your body moves when walking or exercising is a great way to reduce unnecessary strain on your joints. That said, it’s also important to break up prolonged periods of sitting or standing with other types of movement.
  • Stress management. High stress levels can lead to inflammation. Implementing daily stress management techniques (like meditation, journaling or mindful breathing) into your daily routine will calm your nervous system and help reduce inflammation over time. 
  • Quality sleep. Practicing a regular sleep schedule and aiming for at least eight hours of sleep each night can further reduce inflammation. It also allows time for tissue repair and muscle recovery.

The Best Joint Supplements on the Market

Taking individual supplements isn’t necessarily the most effective way to improve joint health – so, what are the best joint supplements on the market? Here are some all-in-one joint supplements that will reduce inflammation, stiffness and pain:

Joint Vibrance by Vibrant Health

Joint Vibrance by Vibrant Health is an all-in-one supplement that includes all of the vitamins and minerals needed to support your joints long-term. 

With four different types of cartilage builders – bovine collage, avian collagen, glucosamine HCL and chondroitin sulfate – it actively repairs and rebuilds your joint cartilage and keeps your bones lubricated. And, with MSM, HLA, turmeric and grapeseed, it helps improve mobility and reduce inflammation. Fortified with antioxidants, it complements a variety of lifestyles and paves the way for smooth, pain-free movement. Whether you’re looking for a preventative supplement or you struggle with arthritis, Joint Vibrance is a fantastic choice for overall joint and cartilage health. 

Joint Vibrance stands out for its extensive blend of vitamins and minerals. It’s made with 1000mg of MSM, which is ten times the amount of the other products on the list. Though it’s pricier than other options on the market, rest assured that you’re paying for quality and honest, intentional ingredients. 

  • Best for: overall joint and cartilage health
  • Beneficial supplements: calcium, collagen, glucosamine, hyaluronic acid, magnesium, manganese, MSM, turmeric, vitamin C, zinc
  • Price: $55.20, $2.62 per serving
  • Certifications: Non-GMO
  • Free of: gluten, soy, dairy, shellfish
Shop Joint Vibrance, the best supplement for overall joint health

Physio Flex Pro

Physio Flex Pro is comprised of a research-based formula that uses natural ingredients to nourish and lubricate your joints while relieving pain and protecting cartilage. A combination of turmeric, ginger, bromelain and selenium fights inflammation and swelling while MSM and chondroitin build and strengthen your cartilage, ligaments, tendons and bones.  

Recommended by physical therapists and approved by the World Orthopedic Group, Physio Flex Pro is an ideal choice for anyone concerned with stiffness, achiness and pain. 

Note that Physio Flex Pro does contain shellfish, and it is unclear if it’s manufactured in a facility that processes soy and dairy. That said, this may not be an ideal option for those with allergies or food sensitivities.

  • Best for: stiffness, achiness and pain
  • Beneficial supplements: black pepper extract, bromelain, chondroitin, ginger, glucosamine, MSM, selenium, turmeric
  • Price: $59.95, $1.99 per serving
  • Certifications: Made in the USA, manufactured in FDA-compliant facilities, approved by the World Orthopedic Group 
  • Free of: gluten

Flex by Performance Lab

Flex by Performance Lab provides natural botanical support for tendons, ligaments and cartilage while nourishing and protecting aching joints against long-term damage. Formulated by specialists using research-backed ingredients, this is a fantastic option for those looking for a gentler, less intense supplement blend.

Flex is recommended for those who often engage in strength training, endurance sports, tech usage or manual labor as well as older adults who are experiencing minor to moderate mobility issues as a result of age. It helps you bounce back over time by offering comfort, protection against damaging enzymes, lubrication and shock absorption via a blend of all-natural ingredients. 

Because it lacks some essential supplements for joint health, Flex may not be ideal for those who struggle with severe pain or arthritis of any kind. It’s best taken for minor aches and pains or as preventative care. 

  • Best for: mobility
  • Beneficial supplements: Boswellia serrata, glucosamine, MSM, phytodroitin, turmeric
  • Price: $49.00, $1.63 per serving
  • Certifications: Non-GMO
  • Free of: synthetic additives, soy, gluten, shellfish, caffeine 

Promote Joint Health With Vibrant Health

It’s true what they say – health is wealth. Prioritizing your physical well-being is the best way to ensure that you can keep up with all of life’s ebbs and flows and take on new challenges with ease and grace.  

Vibrant Health is transforming the definition of wellness and joint health supplements by providing honest, intentional products that fuel your body with clean, no-BS ingredients. Crafted with hyaluronic acid, glucosamine, chondroitin and MSM (among many other essential nutrients and vitamins), Joint Vibrance is your solution to aches, pains and inflammation. 

A healthy life is a happy life. Take the next step in your health journey with Vibrant Health.