Best All In One Supplements in 2023

Amidst all the hustle and bustle of modern life, it can be difficult to prepare healthy meals every day. It’s no wonder that 94% of the United States population is deficient in at least one mineral or vitamin.

Fortunately, all-in-one supplements can help solve this problem. These powerful multivitamins combine multiple nutrients, including vitamins, minerals, antioxidants, omega-3 fatty acids, and probiotics.

So, what is the best all-in-one supplement on the market? In this article, we’ll explain what to look for in an all-in-one supplement and review four top contenders.

What to Look for in an All-in-One Supplement

When choosing the best all-in-one supplement, it’s important to consider the following factors:

• Third-party testing – In the United States, the standards for dietary supplements are much less rigorous than for pharmaceutical medications: The FDA doesn’t examine supplements’ safety or effectiveness. Thus, it’s important to choose supplements that have been safety-tested and verified by third-party organizations. These independent organizations ensure that the supplement contains what it says on the label and is free from harmful contaminants.
• Your unique health and wellness needs – Next, you need to consider your specific health and wellness needs. Different supplements cater to various wellness areas, such as immune support, energy, or overall wellness, so you’ll want to choose one that aligns with your personal goals.
• Bioavailability – Bioavailability assesses the degree and rate at which your body can metabolize the nutrients in a supplement. By choosing a supplement that boasts high bioavailability, you’ll get the most out of its ingredients.
• Nutrient profile – A high-quality, all-in-one supplement should provide a wide range of essential vitamins, minerals, and nutrients.
• Appropriate dosage levels – Before committing to a new supplement, make sure it contains doses of nutrients that are close to the recommended daily values. In order to see specific dosages, you’ll need to avoid proprietary blends, as they don’t disclose the exact amounts of each ingredient.

4 Best All-in-One Supplements on the Market

Now that you know how to evaluate supplements with a discerning eye, let’s dive into four of the best all-in-one options on the market today.

Overview Of All Mentioned Supplements

Supplement Name	Price	Key Features	Pros	Cons
Vibrant Health Trilogy Multivitamin	$44 or $47.50 ($1.46 or $1.58)	Vitamins, minerals, bioavailable omega-3’s, probiotics, triple-tested, vegan option available	Convenient, comprehensive, no proprietary blends	Pricier for vegans
Nature Made Multivitamin Complete	$13.99 ($0.11 / Count)	23 vitamins and minerals, third-party tested, no artificial flavoring, gluten-free, zero preservatives	Affordable, comprehensive, recommended by doctors	Large pill size, unpleasant taste, short shelf life
Thorne Basic Nutrients 2/Day	$38.00 ($0.63/serving)	High-quality ingredients, four rounds of testing, sustainability, high bioavailability, NSF sports certification	Comprehensive, easy to swallow, and sports-friendly	May not be suited to certain people due to vitamin K1 and K2
Hippo7 Vegan Complete Multivitamin	$39.00 ($0.65 per serving)	Vegan, non-GMO, gluten-free, plant-based omega 3’s, 1000% of daily recommended intake of vitamin B12	Vegan-friendly formulation, omega-3s, bioavailable B12	Less comprehensive nutrient profile than other options

Best Overall: Trilogy by Vibrant Health

For 30 years, Vibrant Health has been producing high-quality supplements. Vibrant Health prioritizes truth, transparency, and trust, which is why it never uses proprietary blends. Trilogy is Vibrant Health’s potent multivitamin. It blends three supplements into one, including:

• Multivitamin – Trilogy contains a combination of essential vitamins and minerals, including vitamins A, B12, C, D3, E, selenium, magnesium, and zinc.
• Omega-3’s – Trilogy’s free fatty acid form Omega-3 fish oil is five times more bioavailable than standard fish oil. Fish oil can help support healthy brain function, heart health, and low inflammation levels.
• Probiotics – With 20 billion CFUs from 12 different strains, Trilogy’s probiotics support a broad spectrum of gut-related benefits.

Here are a few more details about this leading all-in-one supplement:

• Form and ease of use – Trilogy comes in capsule form, so it’s flavorless and easy to consume. Vibrant Health recommends taking two supplements daily with food.
• Product quality and safety – Vibrant Health tests Trilogy at multiple stages of manufacturing. In fact, it’s third-party tested and triple-tested for heavy metals and contaminants. Thus, consumers can trust in its purity, potency, and safety.
• Effectiveness – Trilogy’s clinically formulated ingredients come in potent dosages. Since Vibrant Health doesn’t use proprietary blends, you can review the amount of each ingredient to see if it satisfies your dietary needs.
• Suitability – Trilogy has two versions—the standard version contains Omega-3 sourced from mercury-free anchovies, while the vegan version derives its omega-3s from EPA and DHA-rich algae. This supplement is also gluten-free, soy-free, and non-GMO.
• Value for money – Depending on which version you purchase (standard vs. vegan), Trilogy costs $44 or $47.50 per month. If you subscribe for monthly deliveries, you can get this supplement at a discount and enjoy free shipping.

Trilogy is ranked number one on this list because it's comprehensive and convenient. Plus, it’s the only supplement of the four that contains probiotics.

Best For Budget: Multivitamin Tablets with Iron by Nature Made

Coming in second on this list is Nature Made’s Multivitamin Tablets With Iron. Founded in 1971, Nature Made is an established supplement brand that stocks the shelves of many major grocery markets and drug stores.

This all-in-one supplement contains 23 key nutrients, including iron, vitamins A, C, D3, E, K, and B complex. It also features iodine, magnesium, zinc, selenium, copper, manganese, chromium, and molybdenum. As a result, this supplement can deliver many of your essential vitamins and minerals.

However, it’s important to note that you shouldn’t consume more than 45 mg of iron per day. Thus, this supplement’s 18mg of iron may push you over the recommended limit if you already get enough from your diet. With that precaution in mind, let’s take a look at some other details about this multivitamin:

• Form and ease of use – This multivitamin supplement comes in a tablet form. Nature Made suggests taking one tablet per day.
• Product quality and safety – Nature Made sources its nutrients from high-quality ingredients. Additionally, USP third-party tests and verifies its potency and manufacturing process.
• Effectiveness – Thanks to its 23 key nutrients, Nature Made can effectively fill nutrient gaps in your diet. You can find the dosage of each nutrient clearly on its label.
• Suitability – Nature Made’s Multivitamin With Iron may not be suitable for people with blood clotting issues or who are on certain medications. It also contains gelatin, which is not vegan-friendly. However, this supplement is free of gluten and artificial flavors.
• Value for money – You can get a one-month supply of Nature Made’s supplement for just $13.99, making it the most affordable option on this list.

Best For Athletes: Basic Nutrients 2/Day by Thorne

Thone’s Basic Nutrients 2/Day is a comprehensive daily supplement that contains 26 vitamins and minerals, including Vitamins A, C, E, D, K1, K2, and B complex, zinc bis-glycinate, and chromium.

Boasting an NSF for Sport Certification, this supplement is made with athletes in mind. It doesn’t contain any of the 200 substances that are banned by major athletic organizations, from stimulants and steroids to diuretics and masking agents.

Here’s how Thorne Basic Nutrients 2/Day stacks up to the previous competitors:

• Form and ease of use – Thorne Basic Nutrients 2/Day comes in capsules. As its name suggests, a daily dose is two capsules.
• Product quality and safety – As we touched on earlier, this multivitamin is tested and certified by the NSF. It also undergoes four rounds of third-party testing to ensure optimal potency, absorption, and digestibility.
• Effectiveness – Many of Thorne’s multivitamin ingredients stand out for their bioavailability. For example, its zinc comes in the form of zinc bis-glycinate, which is highly absorbable.
• Suitability – Thorne’s daily supplement contains vitamin K, which may interact with anticoagulant drugs. This multivitamin may also be ill-suited for vegans, pregnant women, and people undergoing cancer therapy. Otherwise, this product is free from gluten, dairy, and soy.
• Value for money – Thorne Basic Nutrient’s 2/Day costs $38 for a one-month supply. If you subscribe for monthly deliveries, you can save 20%.

Best for Vegans: Vegan Complete by Hippo7

The last supplement on this list is Vegan Complete by Hippo7. Specially formulated with the needs of plant-based eaters in mind, it contains seven key vitamins, minerals, and nutrients that are hard to get on a vegan diet, including:

1. Vitamin B12
2. Vitamin D
3. Iron
4. Zinc
5. Iodine
6. Calcium
7. DHA and EPA

Here are some specifics about this vegan-friendly multivitamin:

• Form and ease of use – This is a soft gel supplement that’s designed to be taken twice a day with food.
• Product quality and safety – Hippo7 uses the highest-quality ingredients and has its products tested by third-party organizations.
• Effectiveness – This supplement uses methylcobalamin, a natural form of vitamin B12, which is more bioavailable than its synthetic counterpart, cyanocobalamin.
• Suitability – While Vegan Complete is designed for vegans, this cruelty-free supplement is suitable for followers of any diet. Its ingredients are non-GMO and gluten-free. However, you may want to consult with your doctor before taking this supplement if you’re pregnant or taking certain medications.
• Value for money – You can get 30 days of these supplements for $39.00. If you want to replenish your supply each month, you can subscribe to save 25%.

This particular multivitamin stands out for its excellent balance of essential vitamins, minerals, and plant-based omega-3s, making it an ideal choice for those following a vegan diet.

All-in-One Supplements FAQs

Now that you have four excellent options to choose from, let’s answer some of your all-in-one supplement FAQs.

Are all-in-one supplements good?

All-in-one supplements can be a convenient way to ensure you get a broad range of nutrients, especially if your diet lacks variety. However, their effectiveness depends on the quality of the ingredients. It's important to choose a reputable brand and consult with a healthcare provider before starting a new supplement.

Can all-in-one supplements replace a balanced diet?

Just because you’re taking a good all-in-one supplement doesn’t mean that you should slack off and eat junk food for every meal. All-in-one supplements can provide peace of mind when your diet isn’t ideal, but they aren’t a permanent substitute for a varied and balanced diet.

Learn More: Vitamin C: Beyond a Seasonal Ally

How long does it take to see results from taking an all-in-one supplement?

It can take a few weeks to several months to see the full benefits of a new supplement. The specific timeline will depend on your body, the severity of your deficiencies, and the supplement’s formulation. Thus, you should wait a few weeks before determining if a supplement is working as it should.

How should all-in-one supplements be stored?

Typically, you should store your supplements in a dry, cool place. This type of environment can help sustain their potency, safety, and shelf life. However, you can find brand-specific storage guidelines on your supplement’s packaging.

Do all-in-one supplements have expiration dates?

Yes, all-in-one supplements have expiration dates. On average, most supplements have two-year shelf lives.

Are all-in-one supplements suitable for vegetarians or vegans?

Some supplements contain ingredients that have animal derivatives, such as gelatin or fish oil. However, there are also all-in-one supplements specifically formulated for vegetarians and vegans that exclude animal-derived ingredients. These plant-based alternatives use ingredients like plant proteins, algae-based omega-3 oils, and vegetable capsules.