E.coli and other gram-negative bacteria (Pathogenic Bacteria) cause UTIs. 30% of women will have some sort of urinary tract infection this year. Half the women in the world will have a urinary tract infection (UTI) by the age of thirty. Men are by no means immune. Cran Naturelle® 500mg capsules are bio-engineered to have unique potency against E.coli, the primary cause of UTIs. Cran Naturelle® is made from the complete cranberry the fruit solids, juice, seeds and skin. Unlike other cranberry supplements, Cran Naturelle® contains the full synergistic spectrum of the whole cranberry and is not just an extract.